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mRNA based vaccine for SARS-CoV-2

Implementing Organization

Christian Medical College
Principal Investigator
Prof. Alok Srivastava
Christian Medical College

About

This project aims to develop an mRNA based vaccine for SARS-CoV-2.

Patents

NA

Achievements

NA

Outcome / Output

Chemically modified spike mRNA was synthesised with lab designed 5’ and 3’ UTRs and validated functionally. The lyophilised mRNA-lipid nanoparticles were found to be stable at 4° C for up to a week that addresses a critical challenge in the transportation of mRNA vaccines. Promisingly vaccinated animals produced strong immune responses against spike protein and neutralised SARS-CoV-2 pseudovirus.

Publications

NA

Related Research

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Funding Organization
Funding Organization
Department of Biotechnology (DBT)
Quick Information
Focus Area
Vaccine for SARS-CoV-2
Start Year
2020
Sanction Amount
₹ NA
Status
Ongoing
Contact
aloks@cmcvellore.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
No. of Patents
Filed : 00
Grant : 00
Disclaimer: Information available on this portal is sourced from various organizations and is provided for informational purposes only. Users are advised to verify details from the respective official sources.
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