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A novel method to evaluate the quality of antigen-specific T cells in infection and vaccination

Implementing Organization

National Institute of Immunology (NII)
Principal Investigator
Dr Nimesh Gupta
National Institute of Immunology (NII)
Researcher

About

This project aims to develop a novel ex vivo assay to evaluate the functional quality of CD4+ T cells using pathogen-specific proteins and synthetic peptides.

Patents

Filed in India: No. 202111003148

Achievements

NA

Outcome / Output

An ex vivo assay for vaccine efficacy assessment in early phase 1 trial. The assay is applicable for assessing the vaccine efficacy, testing the adjuvants and immune modulators as well as to test the quality of antigen-specific CD4+ T cells induced against vector-borne, respiratory, and communicable human pathogens.

Publications

NA
Funding Organization
Funding Organization
Department of Biotechnology (DBT)
Quick Information
Focus Area
Quality of antigen-specific T cells
Start Year
2020
End Year
2020
Sanction Amount
₹ NA
Status
Completed
Contact
nimesh.gupta@nii.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
No. of Patents
Filed : 00
Grant : 00
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