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Leishmaniasis: target specific approaches to affect host-pathogen interaction and disease process

Implementing Organization

CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata
Principal Investigator
Dr Subrata Adak
Scientist
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CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata

About

Objective: Communication of anti-inflammatory signal from infected macrophage to neighboring cells: Effect on niche creation for Ld infection. Evaluating the potential of host derived Wnt in promoting resistance to Leishmania donovani infection. Cholesterol induced modulation of the leishmanial KMP-11 protein-macrophage interaction. Role of Leishmania derived linoleate in immunoregulation of macrophage. Role of Leishmania y-glutamyl cyclotransferase (ChaC) like protein in pathogenesis of this parasite. Understanding the genome fluidity during the process of gain or loss of virulence in Leishmania.

Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Disease pathology
Start Year
2020
End Year
2025
Status
Completed
Contact
director@iicb.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
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