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Modern innovative solutions for environmental/ occupational lung health challenges using clinical and pre -clinical strategies

Implementing Organization

CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata
CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), Delhi
CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad
CSIR-National Environmental Engineering Research Institute (CSIR–NEERI), Delhi
CSIR-Central Institute of Mining and Fuel Research (CSIR-CIMFR), Dhanbad
Principal Investigator
Dr U Mabalirajan
Scientist
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CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata

About

Objective: a) To identify molecular secretory signatures of disease severity and susceptibility of developing severe lung fibrosis in Coal/metalliferous miners using sputum and Exhaled breath condensate as tools b) Assessing the human exposure to Traffic emissions using Urine and its effects on lung function c) To explore the possible biochemical and molecular mechanisms behind environmental toxicants like Diesel extract particle/Coal mine dust mediated lung pathology. d) DHA supplementation along with inhaled budesonide in 20 more steroid insensitive/resistant asthmatics and 20 steroid insensitive COPD patients as a continuation of CRISP-NCP Project e) Effects of key environmental pollutants like traffic emission, cigarette smoke, Biomass smoke in Traffic sergeants/auto drivers, smokers with or without COPD, village women who use Biomass fuel as primary fuel for cooking on ex vivo steroid insensitivity and in vivo steroid insensitivity in mice models.

Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Earth, Atmosphere & Environment Sciences
Focus Area
Environmental & occupational lung health challenges
Start Year
2020
End Year
2025
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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