Central Food Technological Research Institute (CFTRI)
CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow
CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad
Scientist
Central Food Technological Research Institute (CFTRI)
Objective: Evaluating the role of SREBPs and SREBP inhibition in experimental model of NAFLD using ApoE deficient mice. Histological and immunohistochemical analysis of the fatty liver. Determining the effect of SREBP inhibition in HSCs and food bioactive binding induced changes in SREBP stability. Determining the initial toxicity, nutridynamics and nutrikinetics of food SREBP inhibitors. Determining the initial toxicity, nutridynamics and nutrikinetics of food SREBP inhibitors. Determining the effect of SREBP inhibition in HSCs and food bioactive binding induced changes in SREBP stability. Histological and immunohistochemical analysis of the fatty liver. Evaluating the role of SREBPs and SREBP inhibition in experimental model of NAFLD using ApoE deficient mice.
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