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Transgenerational effect of paternal and maternal vitamin B12 deficiency

Implementing Organization

Principal Investigator
Dr Shantanu Sengupta
Scientist
|
CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), New Delhi

About

Objective: Determine the changes in epigenetic modification, transcriptomic, proteomic and metabolomic profile in Liver and skeletal muscle in pups born to paternal vitamin B 12 deficient rats. To evaluate if vitamin B12 deficiency induced alteration of lipid levels are directly mediated by PPAR a. Compare the pathways and processes affected by maternal and paternal vitamin B 12 deficiency and identify the commonality or differences there of to find a common/differential mechanism for the phenotypic changes.

Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Study of vitamin deficiency in animal model
Start Year
2020
End Year
2023
Status
Completed
Contact
shantanus@igib.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
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