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Transgenerational effect of paternal and maternal vitamin B12 deficiency

Implementing Organization

CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), New Delhi
Principal Investigator
Dr Shantanu Sengupta
Scientist
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CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), New Delhi

About

Objective: Determine the changes in epigenetic modification, transcriptomic, proteomic and metabolomic profile in Liver and skeletal muscle in pups born to paternal vitamin B 12 deficient rats. To evaluate if vitamin B12 deficiency induced alteration of lipid levels are directly mediated by PPAR a. Compare the pathways and processes affected by maternal and paternal vitamin B 12 deficiency and identify the commonality or differences there of to find a common/differential mechanism for the phenotypic changes.

Related Research

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Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Study of vitamin deficiency in animal model
Start Year
2020
End Year
2023
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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