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Mechanism of action of spermidine in pathogenesis of Salmonella, Shigella and Staphylococcus

Implementing Organization

CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh
Principal Investigator
Dr Dipak Dutta
Scientist
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CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh

About

Objective: Unravelling how spermidine over-accumulation in the Salmonella AspeG strain blocks intracellular replication; Showing the link between spermidine over-accumulation and superoxide production in the pathogens; Demonstrating how spermidine over-accumulation affects iron-sulfur cluster biogenesis in pathogen; Assessing the advantages or disadvantages of superoxide production and skewed iron homeostasis under spermidine stress in the pathogenesis of Shigella and Staphylococcus.

Related Research

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Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Biogenesis in pathogen
Start Year
2020
End Year
2023
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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