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Study on the effect of a novel quorum sensing inhibitor isolated from Streptomyces sp. as an adjunct therapy molecule against latent and persisters in Mycobacterium tuberculosis

Implementing Organization

CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh
Principal Investigator
Dr Vijay Chintaman Sonawane
Scientist
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CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh

About

Objective: Production, isolation and purification of the QSI molecule, unravelling its structure. iStudy on the effect of the QSI in lowering of MIC of antitubercular drugs by co-administration of QSI. Study on Inhibition of biofilm formation by M. tuberculosis/M. smegmatis in the presence of QSI (in vitro) . (RNS) tolerance in M. tuberculosis. Study on effect of QSI on DOS regulon in M. tuberculosis which is involved in latency.

Related Research

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Funding Organization
Funding Organization
Council of Scientific and Industrial Research
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Molecular medicine for Tuberculosis
Start Year
2020
End Year
2023
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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