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Understanding the mechanism of hemoglobin receptor recycling by Rab GTPases in Leishmania donovani

Implementing Organization

Indian Institute of Technology (IIT), New Delhi
Principal Investigator
Prof. Amitabha Mukhopadhyay
Professor
|
Indian Institute of Technology Delhi (IITD), Delhi
CO-Principal Investigator
Dr C S Dey
Professor
|
Indian Institute of Technology Delhi (IITD), Delhi

About

In this study, investigators will clone and express Rab11 and Rab4 homologs from the Leishmania and try to identify their effectors. Finally, studies will be carried out to understand the role of Rab4 and Rab11 in Hb-receptor recycling pathway in Leishmania using Rab4 or Rab11 knock out parasites or parasites overexpressing dominant negative mutants of Rab4 or Rab11.

Related Research

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Funding Organization
Funding Organization
Department of Science and Technology (DST)
Quick Information
Area of Research
Life Sciences & Biotechnology
Start Year
2022
Sanction Amount
₹ 60.25 L
Status
Ongoing
Contact
amitabha@bioschool.iitd.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
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