Understanding the role of liver-secreted Cysteine-Rich with EGF-like Domains 2 (CRELD2) in diabesity

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Implementing Organization

National Institute of Immunology (NII)

Principal Investigator

Dr Devram Sampat Ghorpade

Scientist

National Institute of Immunology (NII)

About

Diabesity is a health condition used to describe the incidences of diabetes associated with obesity. Diabesity is a major health concern and is a risk factor for the development of the disease comorbidities like cardiovascular diseases, inflammatory bowel diseases, cancers, fatty liver diseases, kidney diseases, etc. This study aims at: (1) Identification of CRELD2 expression pattern in the livers obtained from multiple models of diabesity, (2) Evaluation of the role of hepatic CRELD2 as a metabolic regulator, (3) Delineation of CRELD2-dependant molecular pathways leading to diabesity, and (4) Identification of the human relevance to the study.

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Funding Organization

Department of Science and Technology (DST)

Quick Information

Area of Research

Life Sciences & Biotechnology

Focus Area

Immunology

Start Year

2022

Sanction Amount

₹ 61.22 L

Status

Ongoing

Contact

dev@nii.ac.in

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

No. of Patents

Filed : 00

Grant : 00

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