Fabrication of conjugates of supramolecular self-aggregated Structures: potentials in diagnosis and combination therapy
Implementing Organization
Indian Association for the Cultivation of Science (IACS)
Principal Investigator
Prof. Prasanta K Das
Professor
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Indian Association for the Cultivation of Science (IACS)
About
The proposal aimed to utilise combination therapy by means of exploiting the synergistic effect of cellular transporters as well as co-administration of two or more therapeutic agents (pro-drug-free drug, free drug-free drug, etc.) with a different mechanism of function for treating cancer. The developed self-assembled structures can serve as a functional table scaffold for augmented loading of chemotherapeutic agents while conjugation with highly fluorescent and photostable Carbon Dots (CDs) that may enable real-time tracking and locating of the drug-loaded conjugates as well as serve as a useful tool for pro-drug activation.
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Indian Association for the Cultivation of Science (IACS)
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