A fluorescent cyclic peptide conjugated amphipathic-D diastereomers nanotherapeutics for an early detection and treatment of prostate cancer
Implementing Organization
Panjab University
Principal Investigator
Dr. Gurpal Singh
UGC Assistant Professor
|
Dr SSB University Institute of Chemical Engineering and Technology, Punjab University, Chandigarh
CO-Principal Investigator
Dr. Sanjay Kumar Bhadada
Post Graduate Institute Of Medical Education And Research
CO-Principal Investigator
Dr. Ravi Pratap Barnwal
Panjab University
CO-Principal Investigator
Dr. santosh kumar
Post Graduate Institute Of Medical Education And Research
CO-Principal Investigator
Dr. Rakesh Kapoor
Post Graduate Institute Of Medical Education And Research
About
Cancer remains a significant global issue, with around 28.0 million new cases expected by 2040. Prostate cancer is one of the most silent cancers, affecting approximately 30% of all major cancers in men. Detecting and treating malignant growth simultaneously is crucial for successful treatment. Current imaging methods, such as computer tomography, ultrasound, positron emission tomography, and magnetic resonance imaging, lack quantification of tumor volume. Peptide treatment offers a promising alternative due to its low molecular weight, low toxicity, and ability to specifically target cancer cells. An amide-linked fluorescent cyclic peptide-amphipathic-D diastereosmers could improve detection and treatment efficacy by expanding prognosis and repressing malignant growth progression. These nanoparticles could be entrapped in PLA-PEG to improve stability and delivery of peptide payloads to tumor environments.
Panjab University
UGC Assistant Professor
Acces sibility Controls