Multifaceted therapy for cardiac regeneration post infarction through delivery of nucleic acids and bioactives via targeted nanocarriers
Implementing Organization
Central University of Kerala
Principal Investigator
Dr. Virendra Gajbhiye
Scientist E
|
Agharkar Research Institute, Maharashtra
CO-Principal Investigator
Dr. Dhananjay Bodas
Agharkar Research Institute
About
Myocardial Infarction (MI) is the leading cause of death in cardiovascular diseases, causing cardiac cell death, loss of functionality, damaged blood vessels, and inflammation. Current treatments are temporary and cannot influence cellular processes like apoptosis, proliferation, inflammation, and vascularization. A multifaceted therapy, including gene therapy, is needed to address MI. MiRNAs play a role in cardiovascular development and disease, but clinical translation is challenging due to multiple target genes and low uptake. Recently, nanoparticles (NPs) have been synthesized to prevent hypoxia/reperfusion-induced apoptosis and induce proliferation.
Science and Engineering Research Board (SERB), New Delhi
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Molecular Biology, Nanobioscience
Start Year
2023
End Year
2025
Sanction Amount
₹ 59.01 L
Status
Completed
Contact
thejaswinivenkatesh5@gmail.com
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed :00
Grant :00
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