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Surface Engineering of Biomedical Implants for the Prevention of MDR Infection

Implementing Organization

Principal Investigator
Dr. Selvakumar Murugesan
National Institute Of Technology, Mangalore, Karnataka, 575025

Project Overview

Bacterial infections in biomedical implants cause severe damage and lead to implant failure, surgery, and re-implantation. Current antibiotics are ineffective due to their limited ability to reach damaged tissue, MDR development by bacteria, and toxic side effects. A new project aims to develop a novel coating formulation using natural polyphenol tannic acid, engineered spider silk protein, and 2D-nanomaterial MXenes for synergistic triple-mode antibacterial action. The formulation will be extended to scaffolds and studied for biofilm formation and antimicrobial characteristics using various assays. This will lead to a universal low-cost coating technology for various medical substrates.
Funding Organization
Funding Organization
Department of Science and Technology (DST)
Quick Information
Focus Area
Antimicrobial Strategies
Start Year
2023
End Year
2026
Sanction Amount
₹ 44.34 L
Status
Ongoing
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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