Fabrication of three-dimensional nanocellulose-based multifunctional materials for tissue engineering and regenerative medicine applications
Implementing Organization
Mahatma Gandhi University
Principal Investigator
Prof. Sabu Thomas
Mahatma Gandhi University
CO-Principal Investigator
Dr. Nandakumar Kalarikkal
Mahatma Gandhi University
CO-Principal Investigator
Dr. Raji V
Mahatma Gandhi University
About
Tissue engineering is a field of biomedical research that focuses on developing therapeutic procedures using functional materials that influence biological systems. Artificial extracellular matrices (ECMs) based on biomaterials and biopolymers can generate or stimulate specific biological functions by regulating cell behavior. However, challenges remain, such as the biomimicry of natural ECM architectures. The current project aims to develop nanocellulose-based bio-mimicking structures for tissue engineering and regenerative medicines. Nanocellulose, such as bacterial cellulose BC and plant cellulose, has unique properties and potential applications in wound dressing materials, burns, artificial skin, and tissue regeneration. The study aims to identify novel cellulose-producing bacterial strains and develop genetically engineered microbial strains for improved BC production.