Development of bi-modal transvaginal probe and evaluation of its diagnostic accuracy for a non-invasive AI-based detection of preinvasive cervical lesion in comparison to standard colposcopy in screen positive patients

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Implementing Organization

Principal Investigator

Dr. Arpitha A

Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER) Pondicherry

CO-Principal Investigator

Dr. s Murali

Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry

CO-Principal Investigator

Dr. sreekumaran Nair N

Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry

CO-Principal Investigator

Dr. Uttam Mrinal Pal

Indian Institute of Information Technology, Design And Manufacturing, Chennai, Tamil Nadu

About

Cervical cancer is the fourth leading cause of mortality globally, with slow progression taking about ten years. Current techniques, such as cytology and colposcopy, are costly and require skilled workers. A transvaginal probe has been proposed to estimate cancer biomarkers like glycogen, Protoporphyrin IX, HbO2, and Hb, to differentiate cancerous tissues from normal ones. The probe uses autofluorescence and multispectral diffuse reflectance spectroscopy to detect an increase in porphyrin and target isosbestic points for HbO2 and Hb. The probe also quantifies protein, glycogen, and nuclear index on the cervix's peripheral tissue, distinguishing pre-cervical cancer from normal cases.

Source

science and Engineering Research Board (sERB), DsT

Related Research

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Funding Organization

Anusandhan National Research Foundation (ANRF)

Quick Information

Area of Research

Life Sciences & Biotechnology

Focus Area

Obstetrics and Gynaecology

Start Year

2024

End Year

2027

Sanction Amount

₹ 33.42 L

Status

Ongoing

Contact

drarpithagynonco@gmail.com

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

No. of Patents

Filed : 00

Grant : 00

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