Research Projects

Stem cells have the potential to self-renew and differentiate into various specialized cell types, making them a promising option for regenerative medicine. However, the efficiency and efficacy of stem cell differentiation are limiting factors, as undifferentiated stem cells may lead to teratoma development. Therefore, measures to improve the directed differentiation efficiency of stem cells into specific cell types are urgently needed. Nanomaterials offer great promise in enhancing the effectiveness of current treatments and paving the way for new clinical breakthroughs. Recent research has shown that nanomaterials can promote stem cell proliferation and differentiation, and scientists are actively investigating the mechanisms by which nanomaterials influence stem cell differentiation. The proposed approach uses biogenic carbon quantum dots (CQDs) to overcome toxicity associated with chemical synthesis and design CQDs from biowaste in a green chemistry approach. These CQDs possess photoluminescence characteristics, allowing for vivid imaging of MSCs and potential cell signaling for migration and differentiation without inductive factors. The project aims to synthesize and characterize CQDs from biowaste, assess their biocompatibility through in vitro assays, and explore their potential for stem cell imaging, migration, and differentiation. In conclusion, the project develops biogenic carbon dots for stem cell biology, allowing stem cell imaging, migration, and differentiation without inductive factors. CQDs are photoluminescent and biocompatible, making them ideal for imaging and commercialization.