Design and Development of Catalytic Enyne Metathesis Type Cycloisomerization Reaction for the Synthesis of Functionalized Heterocycles, Polycyclic (hetero)aromatic Compounds and All Carbon Containing Tetrasubstituted Olefins
Implementing Organization
Banaras Hindu University
Principal Investigator
Dr. Ashok Kumar Basak
Banaras Hindu University
Project Overview
The proposed research project describes our working hypothesis and initial results towards the development of enyne metathesis type novel cycloisomerization chemistry using inexpensive metal triflate as a catalyst which will deliver highly functionalized heterocycles, polycyclic (hetero)aromatic compounds in step- and atom-economic manner. Our work also demonstrated a new avenue for the stereoselective synthesis of all carbon containing tetrasubstituted olefins. Our proposal shows the initial results of a novel domino intramolecular enyne metathesis-dipolar cycloaddition reaction which generates functionalized heterocyclic compounds. Development of a cascade 1,5-hydride transfer annulation-enyne metathesis reaction has also been included in the proposal.
Banaras Hindu University
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