Transition metal-catalyzed fluorine insertion in small organic molecules
Implementing Organization
CSIR-Central Drug Research Institute (CSIR-CDRI), Uttar Pradesh
Principal Investigator
Dr. Nilanjana Majumdar
CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow
Project Overview
A new concept has been proposed for the introduction of fluorine as well as various other fluorinated moieties in small organic molecules using transition-metal catalysis. The work will be explored for the introduction of “F”, “CF3”, “OCF3”, “SCF3” and more. For the asymmetric approach, to achieve the best results, various chiral ligands will be synthesized. The proposed concept would be able to avail important outcomes that would be useful for practical applications.