Prebiotic protein synthesis revealing the mystery of Origins of Life

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Implementing Organization

Gandhi Institute of Technology and Management (GITAM)

Principal Investigator

Dr. Shibaji Basak

Gandhi Institute of Technology and Management (GITAM)

About

The study aims to explore the origins of proteins, which became crucial cellular machinery on early Earth. The emergence of living systems from a non-living prebiotic soup remains a mystery. Modern protein synthesis relies on a complex ribosome, and it is unlikely that anything similar existed on Earth 3-4 billion years ago. The building blocks of life, such as amino acids and nucleobase, were likely present on prebiotic Earth. Self-assembled nano-fibers of peptide/amino acid-nucleobase conjugate molecules will be tested as a template for prebiotic protein synthesis. The selected peptides/proteins will be studied inside vesicles to investigate prebiotic catalysis and its impact on protocellular survivability.

Source

Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24

Related Research

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Funding Organization

Science and Engineering Research Board (SERB), New Delhi

Anusandhan National Research Foundation (ANRF)

Quick Information

Area of Research

Life Sciences & Biotechnology

Focus Area

Astrobiology, Biochemistry

Start Year

2023

End Year

2025

Sanction Amount

₹ 30.49 L

Status

Completed

Contact

shibajibasak@gmail.com

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

No. of Patents

Filed : 00

Grant : 00

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Research Projects