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Prebiotic protein synthesis revealing the mystery of Origins of Life

Implementing Organization

Gandhi Institute of Technology and Management (GITAM)
Principal Investigator
Dr. Shibaji Basak
Gandhi Institute of Technology and Management (GITAM)

About

The study aims to explore the origins of proteins, which became crucial cellular machinery on early Earth. The emergence of living systems from a non-living prebiotic soup remains a mystery. Modern protein synthesis relies on a complex ribosome, and it is unlikely that anything similar existed on Earth 3-4 billion years ago. The building blocks of life, such as amino acids and nucleobase, were likely present on prebiotic Earth. Self-assembled nano-fibers of peptide/amino acid-nucleobase conjugate molecules will be tested as a template for prebiotic protein synthesis. The selected peptides/proteins will be studied inside vesicles to investigate prebiotic catalysis and its impact on protocellular survivability.
Funding Organization
Funding Organization
Science and Engineering Research Board (SERB), New Delhi
Anusandhan National Research Foundation (ANRF)
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Astrobiology, Biochemistry
Start Year
2023
End Year
2025
Sanction Amount
₹ 30.49 L
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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