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Targeting Artemisinin-Resistant Malaria through Innovative Plasmodium falciparum GCN5 HAT Inhibitors

Implementing Organization

Indian Institute of Science
Principal Investigator
Dr. Neha Sharma
Indian Institute of Science

About

Plasmodium falciparum, which causes malaria, is still a serious threat to world health, and drug resistance makes it difficult to treat it effectively. In P. falciparum, histone acetyltransferase GCN5 (HAT: GCN5) has recently come to light as a crucial factor in the regulation of genes linked to artemisinin resistance and stress response. This study proposal sought to develop novel PfGCN5 inhibitors that would interfere with the gene regulatory functions of this protein and improve the effectiveness of malaria treatment.

Source

Source
Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24

Related Research

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Funding Organization
Funding Organization
Science and Engineering Research Board (SERB), New Delhi
Anusandhan National Research Foundation (ANRF)
Quick Information
Area of Research
Medical Sciences
Focus Area
Antimalarial Drug Development, Epigenetics
Start Year
2024
End Year
2026
Status
Ongoing
Contact
nehasharma0024@gmail.com
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
Disclaimer: Information available on this portal is sourced from various organizations and is provided for informational purposes only. Users are advised to verify details from the respective official sources.
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