Investigation on the regulation by small noncoding RNA RyjB under stresses
Implementing Organization
Indian Institute of Technology (IIT)
Principal Investigator
Dr. Tanmay Dutta
Indian Institute Of Technology (IIT) Delhi
About
Bacterial small RNAs (sRNAs) play a crucial role in gene expression regulation. A novel sRNA, RyjB, is found in all growth phases of Escherichia coli and is an acid stress inducible sRNA. Its expression is regulated by PhoP. RyjB is 100% conserved in pathogens like Salmonella and Shigella sp., which cause common human diseases. Studying RyjB in E. coli will help understand its function in pathogenic infections. Preliminary studies found that RyjB promotes cell survival at low pH, and the global stress regulator RpoS is unnecessary for RyjB expression under normal or stress conditions. Hfq is also nonessential for RyjB.
Source
Source
Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24
Science and Engineering Research Board (SERB), New Delhi
Anusandhan National Research Foundation (ANRF)
Quick Information
Area of Research
Life Sciences & Biotechnology
Start Year
2023
End Year
2026
Sanction Amount
₹ 37.51 L
Status
Ongoing
Contact
dtanmay@chemistry.iitd.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed :00
Grant :00
Disclaimer:
Information available on this portal is sourced from various organizations and is provided for informational purposes only. Users are advised to verify details from the respective official sources.
Please enter your details
Please provide your name and email to continue. Your details are saved in this browser for future use.
Latest Updates
Loading…
⚠️
You are leaving this website
You are about to be redirected to an external website that is not operated by
India Science, Technology & Innovation (ISTI) Portal.
Indian Institute of Technology (IIT)
Acces sibility Controls