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Development of Biomass derived Carbon Quantum Dots as Efficient Catalysts for the Facile Synthesis of Biologically Potent Heterocycles

Implementing Organization

Mohan Lal Sukhadia University, Rajasthan
Principal Investigator
Dr. Shikha Agarwal
Mohan Lal Sukhadia University, Rajasthan

Project Overview

Heterocyclic compounds are crucial in various fields, including polymers, drug discovery, agrochemistry, and supramolecular chemistry. They require sustainable synthetic methodologies to synthesize them, and multicomponent reactions (MCRs) are an efficient pathway for this purpose. Photoluminescent carbon quantum dots (CQDs) were first discovered in 2004 and have gained attention due to their biocompatibility, non-toxicity, easy functionalization, and water solubility. CQDs can be prepared using various methods, including hydrothermal, solvothermal, laser ablation, and electrochemical methods. Green synthesis of CQDs involves using green starting materials like organic natural products, grass, fruit juices, plant leaves, fruit peels, and biomass waste. These materials are easily available, economical, and safer, and have high fluorescence, photocatalytic activity, quantum yield, good photostability, low cytotoxicity, and excellent biocompatibility. However, few scientists have worked on the applications of CQDs as catalysts in MCRs. This study aims to synthesize CQDs from biomass, characterize them using UV-Vis, IR, fluorescence studies, TEM, and XRD, and use them as catalysts in the synthesis of biologically active heterocycles. Analytical tools such as IR, NMR, and Mass spectrometry will be used to characterize the synthesized compounds. The synthesized heterocycles will be studied for in silico, in vitro, and in vivo studies.
Funding Organization
Funding Organization
Science and Engineering Research Board (SERB), New Delhi
Anusandhan National Research Foundation (ANRF)
Quick Information
Area of Research
Chemical Sciences
Start Year
2023
End Year
2026
Sanction Amount
₹ 27.03 L
Status
Ongoing
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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