Research Projects

Tin metal, a group 14 element, has unique reactivity and structural properties, making it a potential candidate for anticancer drugs. stannylene, a less stable low-coordinate sn(II) complex, requires stabilization through electronic and steric factors to study its reactivity and anticancer properties. However, the biological potential of stannylenes has not been studied. The ability to stabilize stannylene in solution and use it for biological applications could lead to new insights. Developing luminescent high-coordinated sn(II) complexes and exploring their biological properties could lead to new pathways in biomedical applications. Fluorescent compounds with low cytotoxicity, photostability, and organelle specificity can help diagnose physiological disorders related to specific organelles and act as real-time tracking bioimaging agents. Fluorescent compounds with high cytotoxic properties can accurately evaluate cell death mechanisms. In bioimaging, tin(IV) compounds are not reported as organelle-specific markers. sn(II/IV) complexes with fluorescent properties and biomedical applications are becoming increasingly popular. Developing tin(IV) complexes with two-photon absorption capacity for cellular imaging can improve images and reduce cell damage. The project aims to synthesize novel and sensitive stannylene systems and their use in biological applications. It also focuses on developing fluorescent active tin(IV) complexes as potential anticancer drugs or bioimaging probes based on their cytotoxic potential. The key factor will be their effect on cell viability, with potent cytotoxicity determining cell death mechanisms.