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Understanding the molecular secrets of antifungal and antibacterial activity of Burkholderia gladioli strain NGJ1 and utilization thereof for disease control in rice

Implementing Organization

National Institute of Plant Genome Research (NIPGR)
Principal Investigator
Dr. Gopaljee Jha
National Institute of Plant Genome Research (NIPGR)
CO-Principal Investigator
Dr. senthilkumar Muthappa
National Institute of Plant Genome Research (NIPGR)

About

The lab at NIPGR in New Delhi has discovered a novel antifungal bacterium, Burkholderia gladioli strain NGJ1, from rice. The bacterium exhibits broad-spectrum mycophagous and antifungal activity on various fungi, including R. solani. It can use fungal biomass as a sole nutrient source and induces cell death. A phage tail-like protein (Bg_9562) is essential for the bacterium's mycophagous activity. Purified Bg_9562 protein can effectively control R. solani infection. NGJ1 also exhibits broad-spectrum antibacterial activity, deploying effector proteins to kill co-habiting bacteria. The lab plans to use bacterial genetics approaches to identify mutants defective in these activities and study the regulatory molecules responsible for these activities. The identified molecules will be used for controlling fungal and bacterial diseases in rice.

Source

Source
Anusandhan National Research Foundation/science and Engineering Research Board (sERB), DsT 2023-24
Funding Organization
Funding Organization
Science and Engineering Research Board (SERB), New Delhi
Anusandhan National Research Foundation (ANRF)
Quick Information
Area of Research
Life Sciences & Biotechnology
Start Year
2023
End Year
2026
Sanction Amount
₹ 58.41 L
Status
Ongoing
Contact
jmsgopal@nipgr.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
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