Research Projects

Organometallic catalysts are essential in facilitating the progress of complex reactions by temporarily associating with substrates. They increase the proximity of reacting centers and allow proper electron density exchange to make or break chemical bonds. They accelerate reactions by reducing energy barriers. 1,1-diaminoazines, with their functional unit (C=N-N=C(NH2)2), are suitable as multidentate ligands for transition metal complex formation. Pyridinylazines carry three nitrogen atoms, resulting in two five-membered rings with immense thermal stability. These catalysts are useful for organocatalysis and heterocyclic synthesis. Using quantum chemical and experimental methods, it was established that neutral azine tautomers are more stable than hydrazones. This class of compounds has numerous heterocyclic applications. The structural features of diaminoazines suggest they can exhibit tridentate ligand properties in organometallic chemistry. The current proposal is to generate many derivatives of 1,1-diaminoazine as pincer ligands and explore their application in organometallic catalysis, including asymmetric reactions. Pincer complexes are a special class of organometallic catalysts, with many applications in organic synthesis. This proposal aims to exploit 1,1-diaminoazines as effective ligands for the generation of pincer complexes and explore their catalytic applications.

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