A unified Total Synthesis of Norditerpene Dilactones
Implementing Organization
Indian Institute Of Technology Kanpur (IITK), Uttar Pradesh
Principal Investigator
Dr. Parthasarathi Subramanian
Indian Institute Of Technology Kanpur (IITK), Uttar Pradesh
Project Overview
This proposal proposes a unified synthetic strategy for the asymmetric total synthesis of norditerpene dilactones. The route involves a cascade palladium-catalyzed dienylation, intramolecular Diels-Alder reaction, and sequential methylations. Substrate-controlled functionalization will ensemble the synthesis. The proposal could significantly impact the synthetic community by demonstrating an efficient method for synthesizing these biologically relevant and structurally complex natural products.
Source
Source
Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24
Indian Institute Of Technology Kanpur (IITK), Uttar Pradesh
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