1,8-Naphthyridines have various pharmacological effects, including being effective DNA intercalates. They alter DNA conformation and inhibit DNA duplication, making them potential anti-cancer agents. To develop potent 1,8-naphthyridine derivatives with other substituted derivatives under greener conditions, researchers aim to synthesize these derivatives under in vitro studies and examine their cytotoxic activity under greener conditions.
Source
Source
Anusandhan National Research Foundation/science and Engineering Research Board (sERB), DsT 2023-24
Osmania University, Hyderabad, Telangana
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