Research Projects

The current proposal highlights a unique CC bond forming reaction between vinyl azides and various in situ generated iminium intermediates under transition metal free conditions. Moreover, the proposed reactions may proceed under mild reaction conditions and yield a number of valuable cyclic/acyclic amines under a redox-neutral atmosphere. Notably, the reaction may proceed via direct insertion of metheyleneamino unit into vinyl azides followed by Schmidt-type reaction and 1,5-hydride transfer sequence. In addition, a straightforward and single step strategy to install methyleneamino unit at - position of saturated N-heterocycle is predicted. Furthermore, asymmetric transformation between vinyl azides and aminals to yield enantiopure amines is anticipated.