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Prototype development of a non-invasive plasmonic fiber sensor using nanomaterials for detection of cortisol salivary biomarker

Implementing Organization

Principal Investigator
Dr. sarika Pal
National Institute Of Technology (NIT) Uttrakhand
CO-Principal Investigator
Prof. Lalit Kumar AwasthiNational Institute Of Technology (NIT) Uttrakhand-246174
Dr. Bela Goyal, All India Institute Of Medical sciences (AIIMs), Rishikesh, Uttarakhand-249202

Project Overview

The study aims to develop a highly sensitive and selective, non-invasive cortisol sensor for point of care diagnostics. Current diagnostic methods rely on laborious and time-consuming procedures, such as lateral flow tests or electrochemistry. The proposed cortisol sensor, which uses surface plasmon resonance (sPR) technology, could provide quick, reliable, label-free, and real-time sensing. However, there is still room for improvement in the sensor's sPR-based sensing characteristics. The research proposal introduces long-range surface plasmon polaritons (LR-sPPs) in fiber optic sensors to control and tune surface plasmon polaritons in fiber more precisely over a wider dynamic range. The study also analyzes the influence of 2D nanomaterials like graphene and antimonene as bio-recognition elements (BRE) on sensing characteristics for plasmonic LR-sPPs in fiber optic sensors. The goal is to achieve miniaturization, low weight, portable, and remote sensing capabilities. The proposed cortisol sensor will be portable, miniaturized, and have a minimal detection limit for POC diagnostics. This sensor will increase performance efficiency and provide a choice for remote sensing with future-generation sensor technology. The prototype will be helpful for POC diagnostics.

Source

Source
Anusandhan National Research Foundation/science and Engineering Research Board (sERB), DsT 2023-24
Funding Organization
Quick Information
Area of Research
Engineering Sciences
Start Date
2024
End Date
2027
Status
ongoing
Contact
sarikapal@nituk.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
00
No. of Patents
Filed : 00
Grant : 00
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