Gandhi Institute Of Technology And Management (Gitam), Andhra Pradesh
Project Overview
The study aims to explore the origins of proteins, which became crucial cellular machinery on early Earth. The emergence of living systems from a non-living prebiotic soup remains a mystery. Modern protein synthesis relies on a complex ribosome, and it is unlikely that anything similar existed on Earth 3-4 billion years ago. The building blocks of life, such as amino acids and nucleobase, were likely present on prebiotic Earth. Self-assembled nano-fibers of peptide/amino acid-nucleobase conjugate molecules will be tested as a template for prebiotic protein synthesis. The selected peptides/proteins will be studied inside vesicles to investigate prebiotic catalysis and its impact on protocellular survivability.
Source
Source
Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24
Gandhi Institute Of Technology And Management (Gitam), Andhra Pradesh
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