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Structural and functional characterization of potential drug target proteins from ESKAPE pathogens

Implementing Organization

CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow
Principal Investigator
Dr Ashish Arora
Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow

Project Overview

Objective: Cloning, expression, and purification of selected targets. Characterization of their folding, solubility and stability . Isotopic labeling and determination of NMR solution structure of selected targets. Crystallization and determination of crystal structure of selected targets. Harnessing of structural information for the design of inhibitors. Testing of new and known inhibitors for enzyme inhibition and antimicrobial activity.

Funding Organization
Funding Organization
Council of Scientific and Industrial Research (CSIR), Government of India
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Characterization of potential drug target
Start Date
2020
End Date
2023
Status
Completed
Contact
director@cdri.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
00
No. of Patents
Filed : 00
Grant : 00
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