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Methylated cfDNA as a pathological biomarker for the development of a CRISPR/Cas based molecular diagnostic tool

This project aims to develop an early-stage diagnostic biosensor for chronic diseases like CKD, CVDs, and T2DM using CRISPR technology. By targeting cell-free DNA (cfDNA) methylation, the biosensor will detect disease progression through genetic anal

Identification of novel biomarkers in ovarian cancer and design of appropriate prognostic probes

The project aims to explore gene signatures for predicting chemotherapy resistance in ovarian cancer (OC). It focuses on isolating exosomes secreted by cancer cells, which play a role in tumor progression, metastasis, and resistance to treatment. Thi

Development of detection system of pre-validated salivary biomarkers to determine the stages and type of cardiovascular disease

This project aims to develop a portable system for early detection of cardiovascular diseases (CVD) by identifying biomarkers from existing datasets. The objectives include:1. Using in silico approaches to identify novel biomarkers and validating the

Developing novel biomarker based test for Rapid diagnosis of Malaria infection as better alternate to current approaches

The current malaria Rapid Diagnostic Tests (RDTs), targeting proteins like LDH, HRP2, Aldolase, and GluDH, have limitations in sensitivity and accuracy. With only two-thirds of reported malaria cases receiving confirmatory tests, there is a critical

Artificial Intelligence assisted surgical procedure for customized patient-specificdental implants using cloud-based automated workflow

Progression from a well validated prototype of a non-invasive, blood-free RBC indices and morphology detector towards a product in the market

Development of non-invasive first-line optoelectronic screening device for Hemoglobin detection. This is project is to convert a working and validated prototype into product which will be certified and be ready to go to market.

Multiplexing for easy and affordable Detection of Myeloid Leukemia (CML & AML-M2)

Problem: In India Leukaemia constitutes 25% of the hematopoietic malignancy, hence the need of the hour to design an indigenous Multiplex, viable prototype which is a quick, accurate, and thermally stable diagnostic assay for detection of two most co

Multi-Modal Sensor System for Prosthetic Hand with Embedded Intelligence

This project proposes to develop a prosthetic hand prototype with anthropomorphic capabilities for stable grasping. This will be achieved through combination of mechanical design and embedded electronics with a multi-modal sensor system consisting of

Field portable bright field microscopic system for real-time air quality monitoring of PM2.5 with simultaneous shape, size, and concentration measurement.

The system analyses ambient air which is sampled through a cyclone separator (CS) with the help of a vacuum pump. The vacuum pump has a flow rate of 13 lpm (litres per minute) collects the PM2.5 from the ambient environment, and it is coupled with th

Design, Development, and Clinical trials of Tooth colored Alumina Dental Braces set

The proposed project will cater to the need of indigenous technology anddevice development in the field of dentistry such as ceramic (Alumina) dentalbraces. Development of Alumina feedstock with optimised composition,morphology, binder type/content a