| India Science, Technology & Innovation

In silico analysis of 10000 genomic sequences of COVID-19 around the world including India to identify genetic variability and potential molecular targets in virus and human

The study proposes to perform the in silico analysis of 10000 genomes around the globe including India of SARS-CoV-2 to identify the genetic variability in terms of mutation as missense, indel and silent.

Section: Life Sciences & Biotechnology (Research Project)

Molecular Beacons-based detection of novel SARS-CoV-2

This project aims to use nucleic acid sequence-based amplification (NASBA) for diagnosis of SARS-CoV-2 infections. In this technique, SARS-CoV-2 genomic RNA will be amplified by the sequential action of reverse transcriptase, RNase H and T7 RNA polym

Section: Life Sciences & Biotechnology (Research Project)

Novel target identification and drug repositioning for COVID-19 based on interaction network, molecular design and machine learning

This project aims to (a) identify relevant targets (both viral and host) by expansive analysis of the viral-host interactome at multiple levels; and (b) to screen for possible drug molecules that effectively inhibits these targets using traditional m

Section: Pharmaceutical Sciences (Research Project)

Optimisation of lockdown, testing and isolating strategies to contain COVID-19 in India

The study primarily aims at modelling the current COVID-19 pandemic to understand its spread in India and to simulate different strategies that affect its future spread and long-term impact. A modified compartmental model will be developed and traine

Section: Medical Sciences (Research Project)

Paper-based Plasmonic Aptamer Linked Immobilised Sorbent Assay (pALISA) for screening COVID-19 disease

This project aims to develop a paper-based point of care testing kit (POTC) for screening both asymptomatic and symptomatic patients.

Section: Chemical Sciences (Research Project)

Rapid and sensitive detection of novel coronavirus (SARS-CoV-2) using isothermal nucleic acid amplification

This project aims to develop two isothermal amplification of nucleic acid such as RT-polymerase spiral reaction (RT-PSR) assays and RT-loop-mediated isothermal amplification (RT-LAMP).

Section: Life Sciences & Biotechnology (Research Project)

Rapid identification of COVID-19 biomarkers in blood plasma using Raman spectroscopy and artificial intelligence

The study is directed at identifying COVID-19 biomarkers in the blood plasma of infected patients.

Section: Medical Sciences (Research Project)

Rapid, affordable, portable SARS-CoV-2 screening kit for resource-limited settings

This project aims to develop a novel coulometric detection platform of COVID-19 virus nucleic acid for rapid (2 to 3 hours), cost-effective (Rs 400 to 500 per sample), sensitive (more than 90%), naked-eyes detection colorimetric detection in resource

Section: Medical Sciences (Research Project)

Re-purposing of approved drugs from DrugBank database for possible treatment of COVID-19 by targeting SARS-CoV-2 main protease

In the current project, the plan is to use extensive computational and biochemical approaches to explore DrugBank database compounds as inhibitors of SARS-CoV-2 main protease.

Section: Pharmaceutical Sciences (Research Project)

Remedial action, knowledge skimming and holistic analysis of COVID-19 (RAKSHAK)

RAKSHAK aims at development of Artificial Intelligence (AI)-based platform for analytics data modelling and insights analysis of epidemiological data for medical and other national emergencies.

Section: Computer Sciences and Information Technology (Research Project)

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In silico analysis of 10000 genomic sequences of COVID-19 around the world including India to identify genetic variability and potential molecular targets in virus and human

Molecular Beacons-based detection of novel SARS-CoV-2

Novel target identification and drug repositioning for COVID-19 based on interaction network, molecular design and machine learning

Optimisation of lockdown, testing and isolating strategies to contain COVID-19 in India

Paper-based Plasmonic Aptamer Linked Immobilised Sorbent Assay (pALISA) for screening COVID-19 disease

Rapid and sensitive detection of novel coronavirus (SARS-CoV-2) using isothermal nucleic acid amplification

Rapid identification of COVID-19 biomarkers in blood plasma using Raman spectroscopy and artificial intelligence

Rapid, affordable, portable SARS-CoV-2 screening kit for resource-limited settings

Re-purposing of approved drugs from DrugBank database for possible treatment of COVID-19 by targeting SARS-CoV-2 main protease

Remedial action, knowledge skimming and holistic analysis of COVID-19 (RAKSHAK)

विज्ञान एवं प्रौद्योगिकी विभाग

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