Abundantly available across India in all seasons Lead molecule: Carbazole Alkaloid (CM-5) medicinal value reported in Charaka Samhita. Non toxic to CD34+ progenitor cell, normal blood cells and astrocytes, normal lung/kidney cell lines from human to monkey. Showed NO acute and chronic toxicity towards normal mice
. Shows anti-proliferative activity against cancer cells(in vitro/ex vivo/ in vivo)
Benefits
In vitor studies with CM-5,Mechanism of Apotosis induced by CM-5, Toxicity of CM-5, In vivo and ex voivo studies with CM-5, Herbal extract enriched with CM-5
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