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Glycolipid Based Niosomal Delivery System for Drugs and Biomolecules

Project Overview

Niosomes, by virtue of its vesicular structure, can house both hydrophilic and hydrophobic molecules within its compartments. By exploring the structure-forming attributes of acidic sophorolipid (a microbial glycolipid) we have developed a carrier system for drug and biomolecule delivery. The versatile system can be synthesized with different charges (+Ve/-Ve), size and physical characteristics.

Benefits

They are highly suitable for the delivery of drugs having poor bioavailability due to low water solubility. A prototype of the system has been tested for the delivery of poorly soluble drug amphotericin B. This preparation can also be used for gene and protein delivery and for bio-imaging purposes.

Source

Quick Information
Thrust Areas
Pharmaceutical Sciences
Focus Area
Niosomal Delivery
Source Title
Output
TRL: Technology Readiness Level
Proof of Concept
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