A Promising Therapeutic Lead from Medicinal Plant: Hope for Targeting Cancer and Cancer Stem like Cells
Implementing Organization
Indian Institute of Chemical Biology (IICB)
Project Overview
Abundantly available across India in all seasons Lead molecule: Carbazole Alkaloid (CM-5) medicinal value reported in Charaka Samhita. Non toxic to CD34+ progenitor cell, normal blood cells and astrocytes, normal lung/kidney cell lines from human to monkey. Showed NO acute and chronic toxicity towards normal mice
. Shows anti-proliferative activity against cancer cells(in vitro/ex vivo/ in vivo)