Dry Powder Inhalation of Particles Containing Anti-tuberculosis Drugs
Implementing Organization
Central Drug Research Institute (CDRI)
Project Overview
Treatment of pulmonary TB with orally-administered drugs is sub-optimal-exposing non-target tissues to toxic drugs and requiring large doses to build up effective concentrations in lungs
. Prolonged dosing is required to build up and maintain effective concentrations in lungs
. Patients remain infectious for considerable periods after initiating drug treatment.