Glycolipid Based Niosomal Delivery System for Drugs and Biomolecules
Implementing Organization
Institute of Microbial Technology (IMTECH)
Institute of Microbial Technology (IMTECH), Chandigarh
About
Niosomes, by virtue of its vesicular structure, can house both hydrophilic and hydrophobic molecules within its compartments. By exploring the structure-forming attributes of acidic sophorolipid (a microbial glycolipid) we have developed a carrier system for drug and biomolecule delivery. The versatile system can be synthesized with different charges (+Ve/-Ve), size and physical characteristics.
Outcome / Output
They are highly suitable for the delivery of drugs having poor bioavailability due to low water solubility. A prototype of the system has been tested for the delivery of poorly soluble drug amphotericin B. This preparation can also be used for gene and protein delivery and for bio-imaging purposes.
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