Institute of Himalayan Bioresource Technology (IHBT)
About
Contributions of CSIR-IHBT
. A thermostable SOD has been identified from a Himalayan polyextremophile plant Potentilla atrosanguinea, which was further engineered by mutation of a single amino acid to enhance the thermostability of the enzyme to twofold. An in vitro expression system was developed in E. coli for enzyme production at pilot scale.
Patents
US6485950, US7037697
Outcome / Output
Unique features of CSIR-IHBT SOD
, SOD tolerates autoclaving [retains~75% of the un-autoclaved activity (specific activity) as measured at 5°C to 10°C], It functions across 0°C to 50°C with varying activities at different assay temperatures, Stable at room temperature, SOD has high demand in cosmetic, food and pharmaceutical industries for end applications, like developing anti-ageing creams, extending shelf-life of fruits and vegetables and during cryo-surgery and preservation of organelles.
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